McKesson Corporation is one of the largest pharmaceutical distributors in the United States, controlling a significant portion of the North American wholesale market alongside Cencora and Cardinal Health. The company operates through four primary segments: U.S. Pharmaceutical, Prescription Technology Solutions (RxTS), Medical-Surgical Solutions, and International. The U.S. Pharmaceutical segment is the core revenue driver, generating approximately 90% of total sales by distributing branded, generic, specialty, and biosimilar drugs to retail national accounts, independent pharmacies, and institutional providers. The Medical-Surgical Solutions segment supplies medical equipment and logistics services to physician offices, surgery centers, and home health agencies. The RxTS segment connects pharmacies, providers, and biopharma companies to address medication access and affordability challenges, while the International segment provides wholesale and retail distribution in Canada and select European markets. McKesson's competitive position is underpinned by its massive scale, extensive distribution network, and strategic partnerships, such as its ClarusONE generic sourcing joint venture with Walmart.
